The research of scientists of the University of Bialystok (UB) and the Medical University of Bialystok has proven that a properly composed mixture of oxithiamine and ketoconazole is more effective in combating pathogens that cause mycoses than using these agents separately.
The work of the team of researchers was coordinated by Dr Adam Tylicki, who said that “the tests carried out showed that the use of a combination of ketoconazole and oxithiamine made it possible to reduce the fungicidal concentration, in relation to the most resistant strains of Malassezia pachydermatis, by 4 orders of magnitude compared to the compounds used separately”.
The use of a mixture of these compounds may increase the effectiveness of the treatment of superficial fungal infections.
The inventors predict that the result of their work can be used in pharmacy, veterinary medicine or in the production of cosmetics.