Scientists from the University of Warsaw (UW), the Institute of Experimental and Clinical Medicine and the National Institute of Medicines has conducted a study of a new organic compound with potential use in the treatment of Alzheimer’s disease. The results of the study were published in the journal Physical Chemistry Chemical Physics.

According to the UW, the investigated compound, either alone or bound to nanometre-sized gold particles, can be used to inhibit the activity of acetylcholinesterase, i.e. the enzyme responsible for the hydrolysis of acetylcholine – a neurotransmitter whose deficiency is observed in Alzheimer’s patients.

The new organic compound was obtained by Dr Anna Zawadzka from the Faculty of Chemistry at the University of Warsaw, and then subjected to comprehensive studies, starting with its crystal structure, through its electrochemical and optical properties, and ending with biological studies.

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https://pubs.rsc.org/en/content/articlelanding/2023/CP/D3CP00767G