A team of scientists led by Professor Dariusz Rakus from the Department of Physiology and Molecular Neurobiology at the University of Wrocław conducted research into the ageing process. The results were published in the latest issue of Aging Cell.

The study shows that a two-week reduction in the rate of glycogen breakdown in the body of two-year-old mice improves behavioural parameters (‘restores memory’), and this effect is evident at the morphological level (neurons regain their youthful appearance) and at the molecular level: the proteome of the hippocampus – a brain structure crucial for memory formation – becomes similar to that of young mice. 

The research was carried out in collaboration with the Nencki Institute of Experimental Biology of the Polish Academy of Sciences (PAN) in Warsaw, the Max-Planck Institute of Biochemistry in Martinsried, Wrocław University of Technology, Wrocław University of Life Sciences and Wrocław Medical University, and the Institute of Immunology and Experimental Therapy of the PAN in Wrocław.

Read more: https://uwr.edu.pl/naukowcy-uwr-pomagaja-zatrzymac-proces-starzenia/