Scientists of the Institute of Organic Chemistry of the Polish Academy of Sciences (PAN) have been developed new, stable fluorescent dyes providing opportunity to observe, for example, proteins related to Parkinson’s or Alzheimer’s disease. The research was financed by the Foundation for Polish Science, and the results were published by the journal Angewandte Chemie.
Polish scientists created dyes in cooperation with chemists from France and Germany. The dyes contain the so-called nitro groups, which previously were thought to suppress fluorescence instead support it.
The essence of the research was the discovery of a method allowing dyes with nitro groups to retain both durability and fluorescence – explains the project manager, Prof. Daniel Gryko, director of the Institute of Organic Chemistry of the Polish Academy of Sciences.