Scientists from the Jagiellonian University in Krakow have published a scientific article in the journal “ACS Applied Materials & Interfaces”, describing their research on a new, multi-functional hybrid hydrogel material dedicated to the reconstruction of bone tissue, in particular small bone defects caused by osteoporosis.

The scientists of the Faculty of Chemistry of the Jagiellonian University emphasize, that the deliberately selected composition of the hydrogel hybrid material “enables its biointegration and creates a convenient biomatrix for colonization by osteoblastic cells. The biopolymer scaffold constructed in this way is chemically cross-linked with a substance of natural origin, and also functions as a system for the controlled delivery of an active substance (alendronate), which plays a key role in the treatment of osteoporosis”.

The presented solution ensures a non-invasive location of the scaffold at the implantation site with maintaining the structure, biological properties and limiting the potential adverse side effects of the therapy – emphasizes the Faculty of Chemistry of the Jagiellonian University.

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https://pubs.acs.org/doi/10.1021/acsami.1c17472