The journal “Nucleic Acids Research” published an article describing the new, very sensitive method of direct DNA crack detection called SensiTive Recognition of Individual DNA Ends (STRIDE) developed at the Department of Cell Biophysics of the Jagiellonian University (UJ) in Krakow.

The authors of the work are Dr Magdalena Kordon, Dr Mirosław Zarębski, Dr Kamil Solarczyk and Prof. Jerzy Dobrucki from the Faculty of Biochemistry, Biophysics and Biotechnology of the Jagiellonian University and scientists from the University of Massachusetts.

The method developed with the participation of Krakow scientists has already found application in the study of endogenous DNA damage in various types of cells and tissues, as well as damage arising in cell aging processes and caused by cytotoxic substances, ionizing radiation and other factors that can cause DNA strand breaks. STRIDE technique is patented and commercialized.
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https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz1118/5674990?guestAccessKey=38d5e304-caa2-422e-9fce-8a9b01f28497